The Peluso 22 251 is a large diaphragm tube condenser microphone which aims for the sound of the vintage Telefunken ELA M 251E, originally designed and built by AKG in Vienna. The 22 251 uses a Chinese-made dual diaphragm/dual backplate capsule with edge terminated design, skinned by the Peluso company with 6 micron mylar. The 22 251 inverts the 6072 tube for shorter path between the capsule and the grid of the tube, as in the original ELA M 251E.

Early models of the 22 251 used a CineMag output transformer, but most microphones were built and shipped with a Tamura transformer based on the AKG T14.

The 22 251 offers 9 selectable polar patterns on the power supply, whereas the original ELA M 251E microphone offered on 3 on the head assembly of the mic.